Anti-parietal cell antibodies and pernicious anemia in patients with type 1 diabetes mellitus and multiethnic background.

Abstract

Anti-parietal cell (APC) antibodies and pernicious anemia (PA) were evaluated in patients with type 1 diabetes (n=75) and in controls. A higher frequency of APC (13.3%) and PA (4%) was found in cases than in controls (p=0.003), associated with other autoimmune diseases (p=0.003), but not with insulin or PTPN22 polymorphisms.

• Authors: Alinna Lage Ferraz Pinto, Joana Rodrigues Dantas, Debora Araujo, Bianca Barone, José Ângelo de Souza Papi, José Egídio Paulo de Oliveira, Lenita Zajdenverg, Melanie Rodacki
• Journal: Diabetes research and clinical practice (Diabetes Res Clin Pract) Vol. 102 Issue 2 Pg. e41-3 (Nov 2013) ISSN: 1872-8227 [Electronic] Ireland
• PMID: 24083984 (Publication Type: Journal Article)
• Copyright: Copyright © 2013. Published by Elsevier Ireland Ltd.

Chemical References

• Autoantibodies
• Insulin
• PTPN22 protein, human
• Protein Tyrosine Phosphatase, Non-Receptor Type 22

Topics

• Adolescent
• Adult
• Anemia, Pernicious (blood, complications)
• Autoantibodies (blood)
• Case-Control Studies
• Diabetes Mellitus, Type 1 (blood, complications)
• Ethnicity
• Female
• Humans
• Insulin (genetics)
• Male
• Parietal Cells, Gastric (immunology)
• Protein Tyrosine Phosphatase, Non-Receptor Type 22 (genetics)
• Young Adult