HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[Food supplements--potential and limits: part 3].

Abstract
Ageing processes are associated with physiological changes, e.g. a reduction of metabolically active body mass and an impaired hunger-satiety regulation, which--combined with chronic diseases and psychosocial problems--significantly increase the risk for malnutrition. However, considering their nutrition and health status elderly people are a very heterogeneous group. The nutrition situation of "young" seniors does generally not differ from the situation of working-age adults while institutionalized elderly people and those in need of care often show signs of a global malnutrition. The critical nutrients in the nutrition of the elderly particularly include vitamin B12 and D. Six percent of all elderly have a manifest and 10 to 30% a functional vitamin B12 deficiency. The main cause is vitamin B12 malabsorption resulting from a type B atrophic gastritis. The functional vitamin B12 deficiency and the associated hyperhomocysteinemia are risk factors for neurodegenerative diseases and accelerate bone loss. With increasing age the vitamin D status is deteriorating. About 50% of the elderly living in private households is deficient in vitamin D; in geriatrics vitamin D deficiency is more the rule than an exception. This is caused by a reduced endogenous biosynthesis, low UVB exposure and a diet low in vitamin D. A vitamin D deficiency increases the risk for falls and fractures as well as the risk for neurodegenerative diseases. Also the overall mortality is increased.
AuthorsAlexander Ströhle, Maike Wolters, Andreas Hahn
JournalMedizinische Monatsschrift fur Pharmazeuten (Med Monatsschr Pharm) Vol. 36 Issue 9 Pg. 324-40; quiz 341-2 (Sep 2013) ISSN: 0342-9601 [Print] Germany
Vernacular TitleNährstoffsupplemente--Möglichkeiten und Grenzen. Teil 3: Supplemente im höheren Lebensalter.
PMID24069646 (Publication Type: English Abstract, Journal Article)
Topics
  • Aged
  • Aged, 80 and over
  • Aging (physiology)
  • Body Composition (physiology)
  • Body Mass Index
  • Dietary Supplements
  • Energy Metabolism (physiology)
  • Germany
  • Humans
  • Middle Aged
  • Nutritional Requirements
  • Population Dynamics
  • Protein-Energy Malnutrition (physiopathology, prevention & control)
  • Risk Factors
  • Social Marketing
  • Vitamin B 12 Deficiency (physiopathology, prevention & control)
  • Vitamin D Deficiency (physiopathology, prevention & control)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: