[UFLC/Q-TOF-MS based analysis on material base of atractylodis macrocephalae rhizoma stir-fried with wheat bran].

Abstract

To establish a fingerprint spectrum for Atractylodis Macrocephalae Rhizoma stir-fried with wheat bran based on UFLC/Q-TOF-MS, and make a principal component analysis (PCA) with Markview software, in order to compare the changes of components between raw and processed Atractylodis Macrocephalae Rhizoma with raw wheat bran as the blank. The results showed that the changed in components raw Atractylodis Macrocephalae Rhizoma and Atractylodis Macrocephalae Rhizoma stir-fried with wheat bran were apparently observed by PCA. Six compounds were identified to have significant changes in mass fraction before and after being stir-fried, namely atractylenolide-I, atractylenolide-II, atractylenolide-III, atractylentrid, atractylon and an unknown compound. Among them, atractylenolide-I and atractylenolide-II generated from dehydration and dehydrogenation of atractylenolide-III may be the material base of Atractylodis Macrocephalae Rhizoma stir-fried with wheat bran for strengthening spleen.

• Authors: Xiao-Bing Cui, Chen-Xiao Shan, Hong-Mei Wen, Wei Li, Hao Wu
• Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (Zhongguo Zhong Yao Za Zhi) Vol. 38 Issue 12 Pg. 1929-33 (Jun 2013) ISSN: 1001-5302 [Print] China
• PMID: 24066586 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Dietary Fiber
• Lactones
• Sesquiterpenes
• atractylenolide I
• atractylenolide II
• atractylenolide III

Topics

• Atractylodes (chemistry)
• Chromatography, Liquid (methods)
• Dietary Fiber
• Lactones (analysis)
• Mass Spectrometry
• Principal Component Analysis
• Sesquiterpenes (analysis)