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Sarcophyolides B-E, new cembranoids from the soft coral Sarcophyton elegans.

Abstract
Four new cembrane-type diterpenoids, sarcophyolides B-E (1-4), along with 11 known analogues were isolated from the soft coral Sarcophyton elegans. The structures of new compounds 1-4 were established on the basis of spectroscopic analysis and chemical conversion. The new cembranoids sarcophyolides B (1) and lobocrasol were found to exhibit potent inhibition against A2780 human ovarian tumor cells.
AuthorsZhifang Xi, Wei Bie, Wei Chen, Dong Liu, Leen van Ofwegen, Peter Proksch, Wenhan Lin
JournalMarine drugs (Mar Drugs) Vol. 11 Issue 9 Pg. 3186-96 (Aug 26 2013) ISSN: 1660-3397 [Electronic] Switzerland
PMID24065160 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Diterpenes
  • cembrane
Topics
  • Animals
  • Anthozoa (chemistry)
  • Cell Line, Tumor
  • Diterpenes (chemistry, pharmacology)
  • Humans

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