Abstract |
Four new cembrane-type diterpenoids, sarcophyolides B-E (1-4), along with 11 known analogues were isolated from the soft coral Sarcophyton elegans. The structures of new compounds 1-4 were established on the basis of spectroscopic analysis and chemical conversion. The new cembranoids sarcophyolides B (1) and lobocrasol were found to exhibit potent inhibition against A2780 human ovarian tumor cells.
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Authors | Zhifang Xi, Wei Bie, Wei Chen, Dong Liu, Leen van Ofwegen, Peter Proksch, Wenhan Lin |
Journal | Marine drugs
(Mar Drugs)
Vol. 11
Issue 9
Pg. 3186-96
(Aug 26 2013)
ISSN: 1660-3397 [Electronic] Switzerland |
PMID | 24065160
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Animals
- Anthozoa
(chemistry)
- Cell Line, Tumor
- Diterpenes
(chemistry, pharmacology)
- Humans
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