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An unusual case of a large fibroepithelial stromal polyp presenting as a nipple mass.

AbstractBACKGROUND:
Fibroepithelial stromal polyps (FESP) are benign lesions that typically occur in the genital area and are known to represent a diagnostic challenge for pathologists. Not only do they have a spectrum of morphological changes that ranges from bland morphology to rather atypical appearances, but they also share morphological features with a number of benign and malignant lesions.This is a report of a rare presentation of a FESP of the breast.
CASE PRESENTATION:
We describe an unusual case of a large polypoid mass arising from the nipple and connected to it by a long pedicle in a female of 45. The lesion comprised spindle and stellate shaped cells with bizarre stromal giant cells. The morphological and immunohistochemical diagnostic features are provided together with a discussion of possible mimics.
CONCLUSION:
FESPs may occur in the female breast. It is important to differentiate the lesion from other benign and malignant spindle cell lesions particularly metaplastic carcinoma.
AuthorsAbeer M Shaaban, E P L Turton, William Merchant
JournalBMC research notes (BMC Res Notes) Vol. 6 Pg. 345 (Aug 30 2013) ISSN: 1756-0500 [Electronic] England
PMID24060090 (Publication Type: Case Reports, Journal Article)
Topics
  • Diagnosis, Differential
  • Female
  • Humans
  • Middle Aged
  • Neoplasms, Fibroepithelial (diagnosis)
  • Nipples (pathology, surgery)
  • Polyps (diagnosis, pathology, surgery)
  • Stromal Cells (pathology)

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