Abstract | INTRODUCTION: CASE REPORT: We report a 75 years-old male patient who presented with acute kidney injury and his serum tested positive for p-ANCA by indirect immunofluoresence with a titer of 1/320. Testing by ELISA demonstrated anti- myeloperoxidase (MPO) specificity with a level of 28.8 IU/mL. His kidney biopsy showed features of ATIN with no glomerular involvement. Treatment with corticosteroids led to improvement of his kidney function and serology for ANCA became negative. In this case report ATIN seems to be associated with ANCA positivity, in the absence of other obvious causes for the acute tubulo-interstitial insult. CONCLUSION:
|
Authors | Kawtar Hassani, Amine Mohamed Hamzi, Mohamed Hassani, Mohamed Benyahia |
Journal | Arab journal of nephrology and transplantation
(Arab J Nephrol Transplant)
Vol. 6
Issue 3
Pg. 177-9
(Sep 2013)
ISSN: 1858-554X [Print] Sudan |
PMID | 24053745
(Publication Type: Case Reports, Journal Article)
|
Chemical References |
- Antibodies, Antineutrophil Cytoplasmic
- Biomarkers
|
Topics |
- Acute Disease
- Aged
- Antibodies, Antineutrophil Cytoplasmic
(blood)
- Biomarkers
(blood)
- Biopsy
- Fluorescent Antibody Technique, Indirect
- Humans
- Kidney
(pathology)
- Male
- Nephritis, Interstitial
(blood, immunology, pathology)
|