TMA: beware of complements.

Abstract

In this issue of Blood, Jodele and colleagues report that defective complement regulation contributes to the development of thrombotic microangiopathy (TMA) after hematopoietic stem cell transplantation (HSCT) with important implications for diagnosis and management of this severe clinical complication.

• Authors: Daniel Ricklin, Douglas B Cines
• Journal: Blood (Blood) Vol. 122 Issue 12 Pg. 1997-9 (Sep 19 2013) ISSN: 1528-0020 [Electronic] United States
• PMID: 24052540 (Publication Type: Journal Article, Comment)

Chemical References

• Complement System Proteins

Topics

• Complement Pathway, Alternative
• Complement System Proteins (genetics)
• Hematopoietic Stem Cell Transplantation (adverse effects)
• Humans
• Thrombotic Microangiopathies (etiology)