A randomised comparison of lidocaine 2% gel and proparacaine 0.5% eye drops in paediatric squint surgery.

Abstract	We conducted a randomised trial comparing lidocaine 2% gel with proparacaine 0.5% eye drops in children having elective squint surgery. One hundred and forty children aged between 3 and 14 years were recruited. The requirement for intra-operative fentanyl and postoperative ibuprofen was significantly less in the lidocaine group compared with the proparacaine group (1 (1.7%) vs 12 (18.5%), p=0.002 and 16 (27.6%) 38 (58.5%), p=0.001, respectively). The incidence of postoperative nausea and vomiting was significantly less in the lidocaine group compared with the proparacaine group (6 (10.3%) vs 16 (24.6%), p=0.04). There were no differences between the groups in terms of incidence and severity of the oculocardiac reflex. We conclude that, compared with proparacaine 0.5% eye drops, a single application of lidocaine 2% gel improves peri-operative analgesia and reduces the incidence of postoperative nausea and vomiting in elective paediatric squint surgery.
Authors	R Sinha, Chandralekha, M Batra, B R Ray, V K Mohan, R Saxena
Journal	Anaesthesia (Anaesthesia) Vol. 68 Issue 7 Pg. 747-52 (Jul 2013) ISSN: 1365-2044 [Electronic] England
PMID	24044387 (Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
Copyright	Anaesthesia © 2013 The Association of Anaesthetists of Great Britain and Ireland.
Chemical References	Anesthetics, Local Gels Ophthalmic Solutions Lidocaine proxymetacaine Propoxycaine
Topics	Adolescent Anesthesia, General Anesthetics, Local (administration & dosage) Child Child, Preschool Female Gels Humans Incidence Lidocaine (administration & dosage) Male Monitoring, Intraoperative Ophthalmic Solutions Ophthalmologic Surgical Procedures (methods) Pain Measurement (drug effects) Pain, Postoperative (epidemiology, prevention & control) Postoperative Nausea and Vomiting (epidemiology) Propoxycaine (administration & dosage) Prospective Studies Reflex, Oculocardiac (drug effects) Strabismus (surgery) Treatment Outcome

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