[Polyarthralgia as an initial symptom of sarcoidosis].

Abstract

A 39 year-old patient consulted his family doctor due to migratory polyarthralgia, with C-reactive protein 7.99mg/dl, ESR 89mm and normal anti-streptolysin O (ASO). A sample was taken for analysis in the Rheumatology Clinic: ACE 72 IU, with normal rheumatoid factor, C-reactive protein and ASO; HLA non-specific. Chest X-ray showed an increased pulmonary interstitial pattern, and his chest-CT showed multiple bilateral pulmonary nodules and mediastinal lymph nodes. A differential diagnosis of lymphoproliferative process was considered. A gallium scintigraphy was performed with no relevant findings. The patient was referred to Thoracic Surgery for a lymph node biopsy by mediastinoscopy, which showed a non-necrotizing granulomatous lymphadenitis consistent with a sarcoidosis. Treatment with prednisone and anti-osteoporosis drugs was started and the patient was evaluated at four months with a new chest X-ray. There was a clinical and radiological remission therefore it was decided to gradually reduce the corticosteroid therapy.

• Authors: M N Requeno-Jarabo, R Amorós-García, I I Murillo-Díaz de Cerio, A Antoñanzas-Lombarte
• Journal: Semergen (Semergen) Vol. 39 Issue 6 Pg. 325-9 (Sep 2013) ISSN: 1578-8865 [Electronic] Spain
• Vernacular Title: Poliartralgia como primer síntoma de sarcoidosis.
• PMID: 24034761 (Publication Type: Case Reports, English Abstract, Journal Article)
• Copyright: Copyright © 2011 Sociedad Española de Médicos de Atención Primaria (SEMERGEN). Publicado por Elsevier España. All rights reserved.

Topics

• Adult
• Arthralgia (etiology)
• Humans
• Male
• Sarcoidosis (complications, diagnosis)