The effect of a dentifrice containing Magnolia extract on established plaque and gingivitis in man: a six-month clinical study.

Abstract

AIM:

The aim was to evaluate the clinical effect of a dentifrice containing 0.3% Magnolia extract on dental plaque and gingivitis.

MATERIAL AND METHODS:

The trial was a 6-month double-blind, stratified, randomized and 2-armed parallel group study. Forty-six subjects in the test group brushed their teeth with a dentifrice containing 0.3% Magnolia extract and 48 subjects in the control group brushed with a placebo dentifrice. Plaque and gingivitis were assessed at baseline, 3 and 6 months.

RESULTS:

There was a significantly larger gingivitis reduction in the Magnolia group than in the control group (0.26 ± 0.11 versus 0.11 ± 0.12) (P < 0.001). There was a greater increase in the total number of healthy gingival units Gingival Index (GI score 0) in the Magnolia group than in the control group (149% versus 31%) and a larger reduction in inflamed gingival units (GI score 2/3) (60% versus 30%). Furthermore, at sites with similar amounts of plaque, less clinical signs of gingival inflammation were observed in the Magnolia group than in the control group.

CONCLUSION:

Six months' unsupervised use of a dentifrice containing 0.3% Magnolia extract resulted in significantly greater gingivitis reduction than a corresponding control dentifrice.

• Authors: M-K Hellström, P Ramberg
• Journal: International journal of dental hygiene (Int J Dent Hyg) Vol. 12 Issue 2 Pg. 96-102 (May 2014) ISSN: 1601-5037 [Electronic] England
• PMID: 24034670 (Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
• Copyright: © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Chemical References

• Cariostatic Agents
• Dentifrices
• Placebos
• Plant Extracts
• Sodium Fluoride

Topics

• Adult
• Aged
• Cariostatic Agents (therapeutic use)
• Dental Plaque (prevention & control)
• Dental Plaque Index
• Dentifrices (therapeutic use)
• Double-Blind Method
• Female
• Follow-Up Studies
• Gingivitis (prevention & control)
• Humans
• Magnolia
• Male
• Middle Aged
• Periodontal Index
• Phytotherapy (methods)
• Placebos
• Plant Extracts (therapeutic use)
• Sodium Fluoride (therapeutic use)
• Toothbrushing (instrumentation)
• Young Adult