Potassium bromide-associated panniculitis.

Abstract

Two cases of panniculitis associated with administration of potassium bromide in dogs are reported. Both dogs were treated with potassium bromide for idiopathic epilepsy for over 1 year. Dose increases in both cases were associated with panniculitis, characterised by painful subcutaneous nodules in a generalised distribution over the trunk. Nodule eruption waxed and waned in one dog and was persistent in the other. In both cases, panniculitis was accompanied by lethargy and pyrexia. Panniculitis, lethargy and pyrexia resolved and failed to recur after discontinuation of potassium bromide. No other cause of panniculitis could be determined for either dog. Panniculitis has been reported after administration of potassium bromide in humans and may be a form of drug-induced erythema nodosum. To the authors' knowledge, these are the first reports of potassium bromide-associated panniculitis in dogs.

• Authors: N A Boynosky, L B Stokking
• Journal: The Journal of small animal practice (J Small Anim Pract) Vol. 55 Issue 12 Pg. 640-2 (Dec 2014) ISSN: 1748-5827 [Electronic] England
• PMID: 24032452 (Publication Type: Case Reports, Journal Article)
• Copyright: © 2013 British Small Animal Veterinary Association.

Chemical References

• Anticonvulsants
• Bromides
• Potassium Compounds
• potassium bromide

Topics

• Animals
• Anticonvulsants (adverse effects, therapeutic use)
• Bromides (adverse effects, therapeutic use)
• Dog Diseases (chemically induced, drug therapy)
• Dogs
• Epilepsy, Generalized (drug therapy, veterinary)
• Female
• Panniculitis (chemically induced, veterinary)
• Potassium Compounds (adverse effects, therapeutic use)