Abstract | OBJECTIVE: METHODS: RESULTS: CONCLUSION: The inhibitory effect of Y-39983 on demyelination is probably due to the inactivation of ROCK substrates, which are important for neurite outgrowth, growth cone collapse and demyelination of oligodendrocytes.
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Authors | Cong Gao, Li Huang, Youming Long, Jianzheng Zheng, Jie Yang, Shuxiang Pu, Longchang Xie |
Journal | Neuroimmunomodulation
(Neuroimmunomodulation)
Vol. 20
Issue 6
Pg. 334-40
( 2013)
ISSN: 1423-0216 [Electronic] Switzerland |
PMID | 24008512
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2013 S. Karger AG, Basel. |
Chemical References |
- Protein Kinase Inhibitors
- Pyridines
- Y-39983
- rho-Associated Kinases
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Topics |
- Animals
- Blotting, Western
- Demyelinating Diseases
(pathology)
- Encephalomyelitis, Autoimmune, Experimental
(enzymology, pathology)
- Female
- Mice
- Microscopy, Electron, Transmission
- Protein Kinase Inhibitors
(pharmacology)
- Pyridines
(pharmacology)
- rho-Associated Kinases
(antagonists & inhibitors)
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