HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Measuring glomerular filtration rate in the intensive care unit: no substitutes please.

Abstract
Acute kidney injury (AKI), due to its increasing incidence, associated morbidity and mortality, and potential for development of chronic kidney disease with acceleration to end-stage renal disease, has become of major interest to nephrologists and critical care physicians. The development of biomarkers to diagnose AKI, quantify risk and predict prognosis is receiving considerable attention. Yet techniques to accurately assess functional changes within patients still rely on the use of an insensitive marker (creatinine), creatinine-based estimating equations and unreliable urinary tests. Therefore, it is critical that functional tests be developed and used in combination with biomarkers, thus allowing improved care in AKI and chronic kidney disease patient populations.
AuthorsBruce A Molitoris
JournalCritical care (London, England) (Crit Care) Vol. 17 Issue 5 Pg. 181 (Sep 04 2013) ISSN: 1466-609X [Electronic] England
PMID24004539 (Publication Type: Journal Article, Comment)
Chemical References
  • Creatinine
Topics
  • Acute Kidney Injury (epidemiology, urine)
  • Creatinine (urine)
  • Critical Illness (epidemiology)
  • Female
  • Glomerular Filtration Rate (physiology)
  • Humans
  • Male
  • Metabolic Clearance Rate (physiology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: