HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

Hemicortical resection and reconstruction using pasteurised autograft for parosteal osteosarcoma of the distal femur.

Abstract
The aim of this study was to assess a specific protocol for the treatment of patients with a parosteal osteosarcoma of the distal femur with limb salvage involving hemicortical resection and reconstruction using recycled pasteurised autograft and internal fixation. Between January 2000 and January 2010, 13 patients with a mean age of 26.5 years (17 to 39) underwent this procedure. All the tumours were staged according to Enneking's criteria: there were eight stage IA tumours and five stage IB tumours. The mean follow-up was 101.6 months (58 to 142), and mean post-operative Musculoskeletal Tumour Society functional score was 88.6% (80% to 100%) at the final follow-up. All the patients had achieved bony union; the mean time to union was 11.2 months (6 to 18). Local recurrence occurred in one patient 27 months post-operatively. No patient had a pulmonary metastasis. A hemicortical procedure for the treatment of a parosteal osteosarcoma is safe and effective. Precise pre-operative planning using MRI is essential in order to define the margins of resection. Although it is a technically demanding procedure, gratifying results make it worthwhile for selected patients.
AuthorsT Liu, Z-Y Liu, Q Zhang, X-S Zhang
JournalThe bone & joint journal (Bone Joint J) Vol. 95-B Issue 9 Pg. 1275-9 (Sep 2013) ISSN: 2049-4408 [Electronic] England
PMID23997145 (Publication Type: Journal Article)
Topics
  • Adolescent
  • Adult
  • Bone Transplantation (methods)
  • Female
  • Femoral Neoplasms (surgery)
  • Follow-Up Studies
  • Humans
  • Male
  • Osteosarcoma (surgery)
  • Pasteurization (methods)
  • Salvage Therapy (methods)
  • Transplantation, Autologous
  • Treatment Outcome
  • Young Adult

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!


Choose Username:
Email:
Password:
Verify Password: