Hemicortical resection and reconstruction using pasteurised autograft for parosteal osteosarcoma of the distal femur.

The aim of this study was to assess a specific protocol for the treatment of patients with a parosteal osteosarcoma of the distal femur with limb salvage involving hemicortical resection and reconstruction using recycled pasteurised autograft and internal fixation. Between January 2000 and January 2010, 13 patients with a mean age of 26.5 years (17 to 39) underwent this procedure. All the tumours were staged according to Enneking's criteria: there were eight stage IA tumours and five stage IB tumours. The mean follow-up was 101.6 months (58 to 142), and mean post-operative Musculoskeletal Tumour Society functional score was 88.6% (80% to 100%) at the final follow-up. All the patients had achieved bony union; the mean time to union was 11.2 months (6 to 18). Local recurrence occurred in one patient 27 months post-operatively. No patient had a pulmonary metastasis. A hemicortical procedure for the treatment of a parosteal osteosarcoma is safe and effective. Precise pre-operative planning using MRI is essential in order to define the margins of resection. Although it is a technically demanding procedure, gratifying results make it worthwhile for selected patients.
AuthorsT Liu, Z-Y Liu, Q Zhang, X-S Zhang
JournalThe bone & joint journal (Bone Joint J) Vol. 95-B Issue 9 Pg. 1275-9 (Sep 2013) ISSN: 2049-4408 [Electronic] England
PMID23997145 (Publication Type: Journal Article)
  • Adolescent
  • Adult
  • Bone Transplantation (methods)
  • Female
  • Femoral Neoplasms (surgery)
  • Follow-Up Studies
  • Humans
  • Male
  • Osteosarcoma (surgery)
  • Pasteurization (methods)
  • Salvage Therapy (methods)
  • Transplantation, Autologous
  • Treatment Outcome
  • Young Adult

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