Abstract | OBJECT: METHODS: Patient-reported outcome measures were collated before and after surgery, using a visual analog scale (VAS) score, 36-Item Short-Form Health Survey (SF-36), Brief Pain Inventory (BPI), and University of Washington Neuropathic Pain Score (UWNPS). RESULTS: Twelve patients were treated over 29 months, receiving contralateral, ventroposterolateral sensory thalamic DBS. Five patients were amputees and 7 had BPAs, all from traumas. A postoperative trial of externalized DBS failed in 1 patient with BPA. Eleven patients proceeded to implantation and gained improvement in pain scores at 12 months. No surgical complications or stimulation side effects were noted. In the amputation group, after 12 months the mean VAS score improved by 90.0% ± 10.0% (p = 0.001), SF-36 by 57.5% ± 97.9% (p = 0.127), UWNPS by 80.4% ± 12.7% (p < 0.001), and BPI by 79.9% ± 14.7% (p < 0.001). In the BPA group, after 12 months the mean VAS score improved by 52.7% ± 30.2% (p < 0.001), SF-36 by 15.6% ± 30.5% (p = 1.000), UWNPS by 26.2% ± 40.8% (p = 0.399), and BPI by 38.4% ± 41.7% (p = 0.018). Mean DBS parameters were 2.5 V, 213 microseconds, and 25 Hz. CONCLUSIONS:
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Authors | Erlick A C Pereira, Sandra G Boccard, Paulo Linhares, Clara Chamadoira, Maria José Rosas, Pedro Abreu, Virgínia Rebelo, Rui Vaz, Tipu Z Aziz |
Journal | Neurosurgical focus
(Neurosurg Focus)
Vol. 35
Issue 3
Pg. E7
(Sep 2013)
ISSN: 1092-0684 [Electronic] United States |
PMID | 23991820
(Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't, Review)
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Topics |
- Adult
- Aged
- Amputation, Surgical
(adverse effects)
- Brachial Plexus
(injuries, pathology)
- Clinical Trials as Topic
(methods)
- Cohort Studies
- Deep Brain Stimulation
(methods)
- Female
- Humans
- Male
- Middle Aged
- Neuralgia
(diagnosis, epidemiology, therapy)
- Pain Measurement
(methods)
- Prospective Studies
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