Recurrence of a functional adrenocortical oncocytoma of borderline malignant potential showing high FDG uptake on 18F-FDG PET/CT.

Abstract

Adrenocortical oncocytoma is a very rare tumor, which is not malignant and nonfunctioning in most cases. We report a case of a 53-year-old male with a 9.8 cm sized hyperfunctioning, well-encapsulated adrenal mass, which exhibited by high FDG uptake on a PET/CT scan. The patient had complained of symptoms of Cushing's syndrome for 4 months. Laparoscopic adrenalectomy was performed and the mass was pathologically confirmed as adrenocortical oncocytoma of uncertain malignant potential. Four years after surgery, the tumor recurred with distant metastases, which was proven by subsequent biopsy. 18F-FDG PET/CT also showed hypermetabolism in the recurred tumor and multiple metastatic lesions. Adrenocortical oncocytoma of borderline malignant potential with high FDG uptake may require long-term follow-up with clinical, hormonal, and imaging evaluations.

• Authors: Seung Hyun Son, Sang-Woo Lee, Bong-Il Song, Yun-Jin Jang, Ji-Young Park, Shin Young Jeong, Byeong-Cheol Ahn, Jaetae Lee
• Journal: Annals of nuclear medicine (Ann Nucl Med) Vol. 28 Issue 1 Pg. 69-73 (Jan 2014) ISSN: 1864-6433 [Electronic] Japan
• PMID: 23990396 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Fluorodeoxyglucose F18

Topics

• Adenoma, Oxyphilic (diagnosis, metabolism, pathology)
• Adrenal Cortex Neoplasms (diagnosis, metabolism, pathology)
• Biological Transport
• Female
• Fluorodeoxyglucose F18
• Humans
• Male
• Middle Aged
• Multimodal Imaging
• Positron-Emission Tomography
• Recurrence
• Tomography, X-Ray Computed