The short-term outcome of three-field minimally invasive esophagectomy for Siewert type I esophagogastric junctional adenocarcinoma.

Abstract

BACKGROUND:

The incidence of esophagogastric junctional adenocarcinoma is increasing, and the surgery is associated with high mortality and morbidity rates. This study aims to evaluate whether three-field minimally invasive surgery promotes outcome as compared with three-incision open surgery.

METHODS:

From January 1, 2009, to March 1, 2012, 114 consecutive patients with Siewert type I esophagogastric junctional adenocarcinoma were involved in this retrospective study. Patients were randomly assigned by a computer-generated randomization sequence to receive either three-incision open esophagectomy or minimally invasive esophagectomy. Details concerning patients and tumor characteristics, surgical procedures, and postoperative outcomes were collected and compared.

RESULTS:

Totally, 59 patients were involved in the open esophagectomy group and 55 in the minimally invasive esophagectomy group. The incidence of pulmonary morbidity (9.09% versus 28.81%) and vocal cord paralysis (0% versus 15.25%) in the minimally invasive group was significantly less than that in the open esophagectomy group. Furthermore, the postoperative life quality in the minimally invasive group was better than that in the open group. Survival at 2 years was 83.6% for the minimally invasive group (46 of 55 patients) and 79.7% for the open esophagectomy group (47 of 59 patients).

CONCLUSIONS:

Minimally invasive esophagectomy could lead to a significant improvement of the short-term benefits for patients with Siewert type I esophagogastric junctional adenocarcinoma.

• Authors: Liu Hong, Yujie Zhang, Hongwei Zhang, Jianjun Yang, Qingchuan Zhao
• Journal: The Annals of thoracic surgery (Ann Thorac Surg) Vol. 96 Issue 5 Pg. 1826-31 (Nov 2013) ISSN: 1552-6259 [Electronic] Netherlands
• PMID: 23987903 (Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2013 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

Topics

• Adenocarcinoma (surgery)
• Adolescent
• Adult
• Aged
• Esophageal Neoplasms (surgery)
• Esophagectomy (methods)
• Esophagogastric Junction
• Female
• Humans
• Male
• Middle Aged
• Minimally Invasive Surgical Procedures
• Retrospective Studies
• Time Factors
• Treatment Outcome
• Young Adult