[Treatment of rheumatoid arthritis with low doses of multi-glycosides of Tripterygium wilfordii].

Abstract

Thirty two cases of rheumatoid arthritis were treated with multi-glycosides of Tripterygium wilfordii (T2) in a dosage of 30 mg daily for 12 weeks. Significant improvements in clinical and laboratory variables were observed. In comparison with the results of routine dose of T2 (60 mg per day) treatment, there was no significant difference to be seen between the two treatment plans. Meanwhile, symptom of rash and slightly alimentary canal lower incidences and milder manifestations of side effects of T2 were found in the patients of low dose group than in that of routine dose group. It is suggested that it is reasonable to choose the dose of 30 mg daily as the routine treatment for rheumatoid arthritis patients.

• Authors: X Tao, Y Sun, N Zhang
• Journal: Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine (Zhong Xi Yi Jie He Za Zhi) Vol. 10 Issue 5 Pg. 289-91, 261-2 (May 1990) ISSN: 0254-9034 [Print] China
• PMID: 2397546 (Publication Type: English Abstract, Journal Article)

Chemical References

• Drugs, Chinese Herbal

Topics

• Adult
• Aged
• Arthritis, Rheumatoid (drug therapy)
• Drugs, Chinese Herbal (administration & dosage, therapeutic use)
• Female
• Humans
• Male
• Middle Aged
• Tripterygium