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Premenstrual syndrome in three generations responds to antidepressants.

Abstract
The author identified the clinical picture of 11 patients with premenstrual complaint in a genealogical tree spanning three generations. Seven patients who satisfied criteria for premenstrual syndrome (PMS) were treated successfully with amitriptyline. The possible role of antidepressant treatment for PMS is discussed. The possibility is raised of genetic predisposition in some subtypes of PMS, particularly those in which depression is a feature.
AuthorsE Taghavi
JournalThe Australian and New Zealand journal of psychiatry (Aust N Z J Psychiatry) Vol. 24 Issue 2 Pg. 276-9 (Jun 1990) ISSN: 0004-8674 [Print] England
PMID2396969 (Publication Type: Journal Article)
Chemical References
  • Amitriptyline
Topics
  • Adult
  • Amitriptyline (therapeutic use)
  • Depressive Disorder (drug therapy, genetics)
  • Female
  • Humans
  • Middle Aged
  • Pedigree
  • Premenstrual Syndrome (drug therapy, genetics)
  • Risk Factors

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