Electroconvulsive therapy and Klinefelter syndrome.

Abstract

Klinefelter syndrome is a common sex chromosome disorder characterized by the presence of 1 or more extra X chromosomes, and the most prevalent karyotype is 47,XXY. Epidemiological studies have showed that patients with Klinefelter syndrome had a significantly increased risk of psychosis. We presented a case of a patient with Klinefelter syndrome who was characterized by psychiatric symptoms. The patients had been refractory to clozapine and sodium valproate, but a remarkable improvement occurred after a cycle of 11 sessions of modified electroconvulsive therapy.

• Authors: Qiang Wei, Xinhui Xie, Yang Chen, Yanghua Tian, Honghao Wang, Keyong Wang, Kai Wang
• Journal: The journal of ECT (J ECT) Vol. 29 Issue 3 Pg. e36-7 (Sep 2013) ISSN: 1533-4112 [Electronic] United States
• PMID: 23965608 (Publication Type: Case Reports, Journal Article)

Topics

• Anesthesia
• Electroconvulsive Therapy (adverse effects, methods)
• Electroencephalography
• Humans
• Klinefelter Syndrome (complications, psychology)
• Male
• Middle Aged
• Psychiatric Status Rating Scales
• Schizophrenia (therapy)
• Schizophrenic Psychology
• Treatment Outcome