A novel and other bioactive secondary metabolites from a marine fungus Penicillium oxalicum 0312F1.

Abstract	A new compound 2-(4-hydroxybenzoyl) quinazolin-4(3H)-one (1) and four known compounds were isolated from a marine fungus Penicillium oxalicum 0312F1. The structure of the new compound 1 was elucidated based on the spectroscopic analysis. Bioactivity assays showed that 2-(4-hydroxybenzyl) quinazolin-4(3H)-one (2) and methyl 4-hydroxyphenylacetate (5) had potent inhibitory activity against tobacco mosaic virus (TMV), and the new compound 1 had moderate inhibitory activity against TMV and human gastric cancer cell SGC-7901.
Authors	Shuo Shen, Wei Li, Jian Wang
Journal	Natural product research (Nat Prod Res) Vol. 27 Issue 24 Pg. 2286-91 ( 2013) ISSN: 1478-6427 [Electronic] England
PMID	23962399 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References	Antiviral Agents
Topics	Antiviral Agents (chemistry, pharmacology) Molecular Structure Penicillium (chemistry) Tobacco Mosaic Virus (drug effects)

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