Intramedullary spinal cord metastasis in renal cell carcinoma: a case report of the surgical experience.

Abstract

Intramedullary spinal cord metastasis (ISCM) from renal cell carcinoma (RCC) is rare manifestation and most of them are treated by adjuvant treatment modalities like radiotherapy. Despite the radio-resistance of RCC itself, focal radiotherapy has been preferred as the first-line treatment modality of ISCM from RCC and only a few cases underwent surgical treatment. We describe a case of ISCM from RCC, which underwent surgical excision and pathologically confirmed. A 44-yr-old man was presented with rapid deterioration of motor weakness during focal radiotherapy for ISCM from RCC. After the surgery for removal of the tumor mass and spinal cord decompression, his motor power was dramatically improved to ambulate by himself. We report the first published Korean case of ISCM from RCC confirmed pathologically and describe our surgical experience and his clinical characteristics.

• Authors: Jeongill Park, Seok-Won Chung, Kyoung-Tae Kim, Dae-Chul Cho, Jeong-Hyun Hwang, Joo-Kyung Sung, Dakeun Lee
• Journal: Journal of Korean medical science (J Korean Med Sci) Vol. 28 Issue 8 Pg. 1253-6 (Aug 2013) ISSN: 1598-6357 [Electronic] Korea (South)
• PMID: 23960457 (Publication Type: Case Reports, Journal Article)

Chemical References

• Vimentin
• Keratins

Topics

• Adult
• Carcinoma, Renal Cell (diagnosis, pathology, surgery)
• Humans
• Immunohistochemistry
• Keratins (metabolism)
• Magnetic Resonance Imaging
• Male
• Motor Activity (physiology)
• Spinal Cord Neoplasms (pathology, secondary, surgery)
• Tomography, X-Ray Computed
• Treatment Outcome
• Vimentin (metabolism)