[Sensitivity of aerobic bacteria and Candida species to chlormidazole hydrochloride in vitro].

Abstract

Over 100 bacterial stains, including Candida sp., gram-positive cocci and some gram-negative bacilli, were tested. The majority of microorganisms was isolated from man. Only one bacterial strain (5 micrograms/mL) and 76% of Candida strains were sensitive to chlormidazole HCl (10 micrograms/mL). It may be assumed that most infections with Candida sp. will respond to therapy with drugs containing chlormidazole HCl. Relatively simple and inexpensive tube test may serve to evaluate microbial sensitivity to this agent, especially in case of isolates from patients.

• Authors: I Krasiejko, L Gajewicz, D Lipnicki
• Journal: Polski tygodnik lekarski (Warsaw, Poland : 1960) (Pol Tyg Lek) 1990 Jan 22-29 Vol. 45 Issue 4-5 Pg. 91-2 ISSN: 0032-3756 [Print] Poland
• Vernacular Title: Oznaczanie wrazliwości bakterii tlenowych i drozdzaków z rodzaju Candida na chlorowodorek chlormidazolu in vitro.
• PMID: 2395759 (Publication Type: Journal Article)

Chemical References

• Anti-Bacterial Agents
• Anti-Infective Agents
• Antifungal Agents
• Benzimidazoles
• chlormidazole

Topics

• Anti-Bacterial Agents
• Anti-Infective Agents
• Antifungal Agents
• Bacteria, Aerobic (drug effects)
• Benzimidazoles (pharmacology)
• Candida (drug effects)
• Microbial Sensitivity Tests