[Comparative study of the effectiveness of immuno-correcting therapy in insulin-dependent diabetes mellitus in children].

Abstract

Forty-seven children suffering from insulin-dependent diabetes mellitus were examined for criteria of the efficacy of the immunocorrecting drugs prodigiosan, sodium nucleinate, decaris and splenin. Certain differences were discovered in the clinicoimmunologic efficiency of the drugs enumerated. The treatment of choice should be conducted on an individual basis under control of the immunologic status with regard to the clinicometabolic effect. The necessity has been shown of including the immunocorrecting remedies into multimodality treatment of diabetes mellitus. Decaris and splenin have been found to possess the greatest immunocorrecting activity in respect of the cellular component of immunity and the highest clinicometabolic efficacy.

• Authors: E B Kravets
• Journal: Pediatriia (Pediatriia) Issue 6 Pg. 18-21 ( 1990) ISSN: 0031-403X [Print] Russia (Federation)
• Vernacular Title: Sravnitel'noe izuchenie éffektivnosti immunokorrigiruiushcheĭ terapii pri insulinzavisimom sakharnom diabete u deteĭ.
• PMID: 2395617 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Adjuvants, Immunologic
• Nucleic Acids
• Polysaccharides, Bacterial
• Thymopoietins
• Thymus Hormones
• Levamisole
• thymopoietin III
• sodium nucleinate
• Prodigiozan

Topics

• Adjuvants, Immunologic (therapeutic use)
• Adolescent
• Child
• Diabetes Mellitus, Type 1 (drug therapy, immunology)
• Drug Evaluation
• Female
• Humans
• Levamisole (therapeutic use)
• Male
• Nucleic Acids (therapeutic use)
• Polysaccharides, Bacterial (therapeutic use)
• Prodigiozan (therapeutic use)
• Thymopoietins (therapeutic use)
• Thymus Hormones (therapeutic use)