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Utility of maternal 6-thioguanine nucleotide levels in predicting neonatal pancytopenia.

Abstract
An infant with pancytopenia was born to a mother who used the common immunosuppressant azathioprine (AZA). Maternal and neonatal blood levels of 6-thioguanine nucleotides (6TGN; metabolite of AZA) were 1890 and 1480 pmol/8 × 10(8) red blood cells, respectively. Maternal 6TGN levels could be useful in predicting neonatal pancytopenia.
AuthorsHidehiko Maruyama, Katsuhiko Tada, Takuzo Fujiwara, Kosuke Ota, Misao Kageyama
JournalAJP reports (AJP Rep) Vol. 3 Issue 1 Pg. 25-8 (May 2013) ISSN: 2157-6998 [Print] United States
PMID23943705 (Publication Type: Case Reports)

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