Abstract |
The present article describes two unrelated cases of progressive myoclonic epilepsy (PME) of the Lafora's disease and Unverricht-Lundborg types who were treated with topiramate (TPM) as add-on therapy for their myoclonus. After the initiation of topiramate therapy both cases responded with marked decrease in myoclonic seizure frequency and improvement of quality of life. Topiramate appears to be a useful alternative agent in cases of PME and could be consider for adjunctive therapy.
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Authors | Caner Feyzi Demir, Hasan Hüseyin Ozdemir, Bülent Müngen |
Journal | Acta medica (Hradec Kralove)
(Acta Medica (Hradec Kralove))
Vol. 56
Issue 1
Pg. 36-8
( 2013)
ISSN: 1211-4286 [Print] Czech Republic |
PMID | 23909054
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Anticonvulsants
- Topiramate
- Fructose
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Topics |
- Anticonvulsants
(therapeutic use)
- Drug Therapy, Combination
- Female
- Fructose
(analogs & derivatives, therapeutic use)
- Humans
- Myoclonic Epilepsies, Progressive
(drug therapy)
- Topiramate
- Young Adult
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