Abstract | PURPOSE: Refractory status epilepticus (RSE) is a life-threatening emergency, demonstrating, by definition, significant pharmacoresistance. We describe five cases of pediatric RSE treated with mild hypothermia. METHODS: Retrospective chart review was performed of records of children who received hypothermia for RSE at two tertiary-care pediatric hospitals between 2009 and 2012. KEY FINDINGS: SIGNIFICANCE: This is the largest pediatric case series reporting treatment of RSE with mild hypothermia. Hypothermia decreased seizure burden during and after pediatric RSE and may prevent RSE relapse.
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Authors | Kristin Guilliams, Max Rosen, Sandra Buttram, John Zempel, Jose Pineda, Barbara Miller, Michael Shoykhet |
Journal | Epilepsia
(Epilepsia)
Vol. 54
Issue 9
Pg. 1586-94
(Sep 2013)
ISSN: 1528-1167 [Electronic] United States |
PMID | 23906244
(Publication Type: Journal Article)
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Copyright | Wiley Periodicals, Inc. © 2013 International League Against Epilepsy. |
Chemical References |
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Topics |
- Adolescent
- Child
- Electroencephalography
(methods)
- Female
- Humans
- Hypothermia, Induced
- Infant
- Male
- Pentobarbital
(therapeutic use)
- Retrospective Studies
- Secondary Prevention
- Seizures
(therapy)
- Status Epilepticus
(therapy)
- Treatment Outcome
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