Immediate "steroid flare" from intraarticular triamcinolone hexacetonide injection: case report and review of the literature.

Abstract	We describe a patient who had an immediate, intense, localized synovitis due to intraarticular triamcinolone hexacetonide injection. The reaction was secondary to rapid intracellular ingestion of the steroid microcrystals as demonstrated by compensated polarized microscopy. We report the unique nature of this patient's response, and we review previous literature regarding "steroid flare" after intraarticular injection.
Authors	R G Berger, W J Yount
Journal	Arthritis and rheumatism (Arthritis Rheum) Vol. 33 Issue 8 Pg. 1284-6 (Aug 1990) ISSN: 0004-3591 [Print] United States
PMID	2390131 (Publication Type: Case Reports, Journal Article)
Chemical References	Anti-Inflammatory Agents Triamcinolone Acetonide triamcinolone hexacetonide
Topics	Adult Anti-Inflammatory Agents Birefringence Crystallization Humans Injections, Intra-Articular Male Synovitis (chemically induced, metabolism) Triamcinolone Acetonide (adverse effects, analogs & derivatives, pharmacokinetics)

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