Neuropeptide K-like immunoreactivity in human dental pulp.

Abstract

Nerve fibres displaying such immunoreactivity were revealed by indirect immunofluorescence. Neuropeptide K-like immunoreactive fibres, entering the pulp within large nerve trunks, were distributed around blood vessels as well as in the stroma. Some immunoreactive fibres were also observed in the para-odontoblastic region. In view of the biological activity of neuropeptide K, it is tentatively proposed that it may act in the dental pulp as a regulatory peptide involved in neurogenic inflammation, blood flow regulation and sensory transmission.

• Authors: A Casasco, A Calligaro, D R Springall, M Casasco, P Poggi, K L Valentino, J M Polak
• Journal: Archives of oral biology (Arch Oral Biol) Vol. 35 Issue 1 Pg. 33-6 ( 1990) ISSN: 0003-9969 [Print] England
• PMID: 2390021 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Neuropeptides
• Tachykinins
• neuropeptide K

Topics

• Blood Vessels (innervation)
• Dental Pulp (analysis, blood supply, innervation)
• Humans
• Immunohistochemistry
• Nerve Fibers (analysis, ultrastructure)
• Neuropeptides (analysis)
• Tachykinins