HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

Guidelines for elderly patients with multimorbidity: how to cope with a dark night without fear.

Abstract
The epidemiological transition has produced a society with a growing number of the elderly affected by multiple chronic diseases which often requires polypharmacy. Despite being the main users of medications, the elderly are largely underrepresented in clinical trials, especially if they have multimorbidity. It follows that the results of these trials are not applicable in the real world and potentially harmful. In order to breach the wall of this complexity, several suggestions have been put forward, from new clinical trial methodology, simulation models, and the use of patient-centered as opposed to disease-centered indicators. It is likely that comparative effectiveness research will accelerate the shift toward a focus on "universal" outcomes on which all diseases exert an effect. I believe that there is no "one-size-fits-all" solution in this area, but two ideas come to my mind. Why do we not invest more in educating our future geriatricians? And why do we not invest in public awareness campaigns?
AuthorsAlessandra Marengoni
JournalAging clinical and experimental research (Aging Clin Exp Res) Vol. 25 Issue 6 Pg. 703-5 (Dec 2013) ISSN: 1720-8319 [Electronic] Italy
PMID23888433 (Publication Type: Journal Article)
Topics
  • Aged
  • Aging (psychology)
  • Clinical Trials as Topic (methods)
  • Comparative Effectiveness Research (methods)
  • Fear
  • Humans
  • Morbidity
  • Patient-Centered Care
  • Practice Guidelines as Topic

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!


Choose Username:
Email:
Password:
Verify Password: