Maternal rhabdomyolysis and twin fetal death associated with gestational diabetes insipidus.

Abstract

BACKGROUND:

Gestational diabetes insipidus is a rare, transient complication of pregnancy typically characterized by polyuria and polydipsia that may lead to mild electrolyte abnormalities. More severe sequelae of gestational diabetes insipidus are uncommon.

CASE:

We present a case of a 25-year-old woman at 23 weeks of gestation in a dichorionic-diamniotic twin pregnancy who developed severe symptomatic gestational diabetes insipidus complicated by rhabdomyolysis and death of both fetuses.

CONCLUSION:

Maternal rhabdomyolysis caused by gestational diabetes insipidus is extremely rare. Early recognition and treatment of gestational diabetes insipidus is necessary to prevent maternal and fetal morbidity and mortality.

• Authors: Joan T Price, Nadav Schwartz
• Journal: Obstetrics and gynecology (Obstet Gynecol) Vol. 122 Issue 2 Pt 2 Pg. 493-495 (Aug 2013) ISSN: 1873-233X [Electronic] United States
• PMID: 23884272 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antidiuretic Agents
• Deamino Arginine Vasopressin

Topics

• Adult
• Antidiuretic Agents (therapeutic use)
• Deamino Arginine Vasopressin (therapeutic use)
• Diabetes Insipidus (complications, diagnosis, drug therapy)
• Female
• Fetal Death (etiology)
• Humans
• Hypernatremia (etiology)
• Polyuria (etiology)
• Pregnancy
• Pregnancy Complications (diagnosis, drug therapy)
• Pregnancy, Twin
• Rhabdomyolysis (etiology)