Abstract | BACKGROUND AND AIMS: The aim of this clinical investigation was to compare clinical and microbiological effectiveness of adjunctive CHX gel in the treatment of periodontitis. MATERIALS AND METHODS: Twenty-four subjects with localized or generalized moderate-to-severe chronic periodontitis underwent scaling and root planing. One tooth in each quadrant with a probing depth of >4 mm was chosen for combined gel and SRP, with contralateral tooth as control (SRP treated site). Clinical assessment was carried out at baseline and 1 and 3 months later; microbial assessment was performed by real-time PCR. Periodontal probing depth ( PPD) was considered as primary outcome. RESULTS: Twenty patients completed the study. Baseline PPDs were 4.90±0.78 and 5.05±0.79 in the SRP and gel groups, respectively (P>0.05), which decreased to 3.67±0.59 and 3.7±0.83 one month after treatment and 3.25±0.65 and 3.38±0.79 three months after treatment. Although values decreased significantly in both groups after one and three months (P=0.001 in the SRP and P=0.001 in the gel group), the inter-group difference was not significant neither at one-month (P=0.47) nor at three-month (P=0.77) intervals. The only clinical parameters exhibiting statistically significant inter-group differences was BOP in both one-month (P=0.004) and three-month (P=0.0001) intervals. All the other clinical measurements showed significant decreases after one and three months in both sites but without inter-group differences. CONCLUSION:
|
Authors | Mohammad Taghi Chitsazi, Atabak Kashefimehr, Reza Pourabbas, Adileh Shirmohammadi, Vadood Ghasemi Barghi, Behrouz Daghigh Azar |
Journal | Journal of dental research, dental clinics, dental prospects
(J Dent Res Dent Clin Dent Prospects)
Vol. 7
Issue 2
Pg. 95-101
( 2013)
ISSN: 2008-210X [Print] Iran |
PMID | 23875088
(Publication Type: Journal Article)
|