Abstract | OBJECTIVE: METHODS: Data were analyzed retrospectively from screening projects that collected data from January 2001 to May 2008 in Trivandrum, India. Women with CIN were appropriately treated with cryotherapy by a trained nurse or physician and followed up for cure, adverse events, and complications. Cure was defined as absence of CIN during any follow-up visit at least 1 year after treatment. RESULTS: Among 236 women identified with CIN and appropriately treated with cryotherapy, 173 (81.6%) were followed up (158 CIN 1 and 15 CIN 2 cases). The percentage cure for CIN 1 and 2 lesions was 93.0% and 86.7% respectively. An odds ratio of 0.2 (95% confidence interval, 0.0-0.9) was observed for treatment received more than 2 months after screening as compared with treatment received within 2 months. Complications were observed in 1.2% of treated women and adverse events (discharge and mild pain) in 26.6%. CONCLUSION: The study affirms that trained mid-level providers can appropriately perform cryotherapy in primary healthcare services and that expanding such services in low-resource settings would increase the availability and accessibility of precancer treatment.
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Authors | Ramani S Wesley, Richard Muwonge, Catherine Sauvaget, Somanathan Thara, Rengaswamy Sankaranarayanan |
Journal | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
(Int J Gynaecol Obstet)
Vol. 123
Issue 1
Pg. 16-20
(Oct 2013)
ISSN: 1879-3479 [Electronic] United States |
PMID | 23870419
(Publication Type: Journal Article)
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Copyright | © 2013. |
Topics |
- Adult
- Cryotherapy
(adverse effects, methods)
- Female
- Follow-Up Studies
- Humans
- India
- Primary Health Care
(methods)
- Retrospective Studies
- Time Factors
- Treatment Outcome
- Uterine Cervical Neoplasms
(pathology, therapy)
- Uterine Cervical Dysplasia
(pathology, therapy)
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