Abstract | BACKGROUND: This single-blinded, prospective, randomized controlled trial compared the efficacy and safety of an oxidized cellulose patch ( Surgicel [Johnson and Johnson]) with conventional procedures for achieving hemostasis in thyroid surgery. STUDY DESIGN: The study included 190 patients scheduled for thyroidectomy. Patients were randomized into 1 conventionally treated ( ligatures and bipolar electrocautery) group (n = 92) and a second group, which additionally received Surgicel (n = 98). RESULTS: CONCLUSIONS: Routine use of an oxidized cellulose hemostatic agent has no advantage over conventional hemostasis and is potentially harmful in thyroid surgery.
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Authors | Moran Amit, Yoav Binenbaum, Jacob T Cohen, Ziv Gil |
Journal | Journal of the American College of Surgeons
(J Am Coll Surg)
Vol. 217
Issue 2
Pg. 221-5
(Aug 2013)
ISSN: 1879-1190 [Electronic] United States |
PMID | 23870217
(Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
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Copyright | Copyright © 2013 American College of Surgeons. Published by Elsevier Inc. All rights reserved. |
Chemical References |
- Cellulose, Oxidized
- Hemostatics
- Surgicel
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Blood Loss, Surgical
(prevention & control)
- Cellulose, Oxidized
(therapeutic use)
- Electrocoagulation
- Female
- Hemostasis, Surgical
(methods)
- Hemostatics
(therapeutic use)
- Humans
- Length of Stay
(statistics & numerical data)
- Ligation
- Male
- Middle Aged
- Postoperative Hemorrhage
(prevention & control)
- Prospective Studies
- Single-Blind Method
- Thyroidectomy
- Treatment Outcome
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