Abstract | BACKGROUND: OBJECTIVE: METHODS: Twenty-five patients with ARF, 25 patients with CRHD and 20 control subjects were included in the study. The TnC levels were analyzed using the enzyme-linked immunosorbent assay method in the ARF group. RESULTS: The TnC levels were lower in the acute carditis group compared with the control group (p < 0.001). The cut-off level was estimated as 2.08 ng/ml for diagnosing carditis with 93.3% sensitivity and 95% specificity. On second analysis, prominent decrease was detected in valve insufficiency patients with markedly elevated TnC levels. In the CRHD group, TnC level was significantly lower in cases with severe valve insufficiency (p < 0.001). CONCLUSIONS:
|
Authors | Zehra Karatas, Tamer Baysal, Hayrullah Alp, Aysun Toker |
Journal | Journal of tropical pediatrics
(J Trop Pediatr)
Vol. 59
Issue 6
Pg. 476-82
(Dec 2013)
ISSN: 1465-3664 [Electronic] England |
PMID | 23868575
(Publication Type: Evaluation Study, Journal Article, Research Support, Non-U.S. Gov't)
|
Chemical References |
- Biomarkers
- Tenascin
- C-Reactive Protein
|
Topics |
- Adolescent
- Biomarkers
(blood)
- C-Reactive Protein
(analysis)
- Case-Control Studies
- Child
- Echocardiography
- Electrocardiography
- Enzyme-Linked Immunosorbent Assay
- Female
- Follow-Up Studies
- Humans
- Male
- Myocarditis
(blood, diagnosis, epidemiology)
- Predictive Value of Tests
- Prognosis
- ROC Curve
- Rheumatic Fever
(blood, diagnosis)
- Rheumatic Heart Disease
(blood, diagnosis)
- Tenascin
(blood)
|