Abstract | INTRODUCTION AND OBJECTIVES: METHODS: 34 coeliac patients, 53 with dermatitis herpetiformis and 42 healthy controls were studied. The mean age was 38.0 +/- 12.1, 32.18 +/- 14.95, 35.33 +/- 10.41 years in CD, dermatitis herpetiformis, and healthy controls, respectively. Bone mineral density of the lumbar spine, the left femoral neck and radius were measured by dual-energy X-ray absorptiometry. Low bone density, osteopenia and osteoporosis were defined as a body mass density (BMD) T-score between 0 and -1, between -1 and -2.5, and under -2.5, respectively. RESULTS: at lumbar region, consisting of dominantly trabecular compartment, a decreased BMD was detected in 49 % (n = 26) patients with dermatitis herpetiformis, 62 % (n = 21) of CD patients, and 29 % (n = 12) of healthy controls, respectively. Lower BMD were measured at the lumbar region in dermatitis herpetiformis and CD compared to healthy subjects (0.993 +/- 0.136 g/cm2 and 0.880 +/- 0.155 g/cm2 vs. 1.056 +/- 0.126 g/cm2; p < 0.01). Density of bones consisting of dominantly cortical compartment (femoral neck) did not differ in dermatitis herpetiformis and healthy subjects. CONCLUSIONS: our results show that a low bone mass is also frequent among patients with dermatitis herpetiformis. Bone mineral content in these patients is significantly lower in those parts of the skeleton which contain more trabecular than cortical bone.
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Authors | Katalin Lorinczy, Márk Juhász, Ágnes Csontos, Bálint Fekete, Orsolya Terjék, Péter L Lakatos, Pál Miheller, Dorottya Kocsis, Sarolta Kárpáti, Zsolt Tulassay, Tamás Zágoni |
Journal | Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva
(Rev Esp Enferm Dig)
Vol. 105
Issue 4
Pg. 187-93
(Apr 2013)
ISSN: 1130-0108 [Print] Spain |
PMID | 23859446
(Publication Type: Journal Article)
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Topics |
- Absorptiometry, Photon
- Bone Density
- Bone Diseases, Metabolic
- Celiac Disease
- Cross-Sectional Studies
- Dermatitis Herpetiformis
- Humans
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