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First confirmation by genotyping of transplacental choriocarcinoma transmission.

Abstract
A mother developed multimetastatic gestational choriocarcinoma 13 months after delivery, and her infant died aged 11 months from the same tumor. The transplacental choriocarcinoma transmission was confirmed by genotyping. Henceforth, we recommend a 2-year maternal human chorionic gonadotropin follow-up after neonatal choriocarcinoma and extensive imaging if the human chorionic gonadotropin rises.
AuthorsPierre-Adrien Bolze, Béatrice Weber, Rosemary A Fisher, Michael J Seckl, François Golfier
JournalAmerican journal of obstetrics and gynecology (Am J Obstet Gynecol) Vol. 209 Issue 4 Pg. e4-6 (Oct 2013) ISSN: 1097-6868 [Electronic] United States
PMID23850527 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
CopyrightCopyright © 2013 Mosby, Inc. All rights reserved.
Chemical References
  • Biomarkers, Tumor
  • Chorionic Gonadotropin
Topics
  • Biomarkers, Tumor
  • Choriocarcinoma (blood, genetics, secondary)
  • Chorionic Gonadotropin (blood)
  • Female
  • Genotype
  • Humans
  • Infant
  • Liver Neoplasms (blood, genetics, secondary)
  • Male
  • Maternal-Fetal Exchange
  • Neoplasm Metastasis
  • Pregnancy
  • Pregnancy Complications, Neoplastic (blood, genetics, pathology)
  • Uterine Neoplasms (blood, genetics, pathology)

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