HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Multi-institutional analysis of long-term symptom resolution after cholecystectomy for biliary dyskinesia in children.

AbstractPURPOSE:
Current literature for resolution of abdominal pain after cholecystectomy in children with biliary dyskinesia shows variable outcomes. We sought to compare early outcomes with long-term symptom resolution in children.
METHODS:
Telephone surveys were conducted on children who underwent cholecystectomy for biliary dyskinesia between January 2000 and January 2011 at two centers. Retrospective review was performed to obtain demographics and short-term outcomes.
RESULTS:
Charts of 105 patients' age 7.9-19 years were reviewed; 80.9 % were female. All were symptomatic with an ejection fraction (EF) <35 % or pain with cholecystokinin administration. At the postoperative visit, 76.1 % had resolution of symptoms. Fifty-six (53.3 %) patients were available for follow-up at median 3.7 (1.1-10.7) years. Of these, 34 (60.7 %) reported no ongoing abdominal pain. Of the 22 patients with persistent symptoms, satisfaction score was 7.3 ± 2.7 (scale of 1-10) and 19 (86.4 %) were glad that they had a cholecystectomy performed. EF, body mass index percentile (BMI %), and pain with cholecystokinin (CCK) were not predictive of ongoing pain at either follow-up periods.
CONCLUSION:
Short-term symptom resolution in children undergoing cholecystectomy for biliary dyskinesia is not reflective of long-term results. Neither EF, BMI % nor pain with CCK was predictive of symptom resolution. The majority of patients with ongoing complaints do not regret cholecystectomy.
AuthorsE Marty Knott, Frankie B Fike, Alessandra C Gasior, Robert Cusick, Evan Brownie, Shawn D St Peter, Kenneth S Azarow
JournalPediatric surgery international (Pediatr Surg Int) Vol. 29 Issue 12 Pg. 1243-7 (Dec 2013) ISSN: 1437-9813 [Electronic] Germany
PMID23846453 (Publication Type: Journal Article, Multicenter Study)
Topics
  • Abdominal Pain (complications)
  • Adolescent
  • Adult
  • Biliary Dyskinesia (complications, surgery)
  • Body Mass Index
  • Child
  • Cholecystectomy (methods)
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Patient Satisfaction (statistics & numerical data)
  • Postoperative Period
  • Treatment Outcome
  • Young Adult

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: