Abstract |
We investigated the effects of 10 cmH2O positive end-expiratory pressure on cerebral haemodynamics and cerebral oxygenation in patients undergoing laparoscopic lower abdominal surgery in the 30° Trendelenburg position during desflurane anaesthesia. Twenty-six patients were enrolled in this study. After anaesthesia induction, pneumoperitoneum was applied in Trendelenburg position. Twenty minutes later, positive end-expiratory pressure was applied. There was no change in regional cerebral oxygen saturation (p = 0.376). Cerebral perfusion pressure decreased significantly over time (p < 0.001) and positive end-expiratory pressure caused a further decrease in cerebral perfusion pressure (p = 0.036). The application of 10 cmH2O positive end-expiratory pressure during pneumoperitoneum in the Trendelenburg position preserved regional cerebral oxygen saturation, but cerebral perfusion pressure decreased significantly due to its secondary haemodynamic effects.
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Authors | Y Y Jo, J Y Lee, M G Lee, H J Kwak |
Journal | Anaesthesia
(Anaesthesia)
Vol. 68
Issue 9
Pg. 938-43
(Sep 2013)
ISSN: 1365-2044 [Electronic] England |
PMID | 23841822
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | © 2013 The Association of Anaesthetists of Great Britain and Ireland. |
Chemical References |
- Anesthetics, Inhalation
- Desflurane
- Isoflurane
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Topics |
- Abdomen
(surgery)
- Adult
- Aged
- Anesthetics, Inhalation
- Cerebrovascular Circulation
(physiology)
- Desflurane
- Female
- Head-Down Tilt
(physiology)
- Hemodynamics
(physiology)
- Humans
- Isoflurane
(analogs & derivatives)
- Laparoscopy
(methods)
- Male
- Middle Aged
- Pneumoperitoneum, Artificial
(methods)
- Positive-Pressure Respiration
(methods)
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