[Systematic review on control of swelling and trismus after extraction of impacted mandibular third molar by dexamethasone pericoronal injection].

Abstract

OBJECTIVE:

To assess the efficacy of Dexamethasone (DM) pericoronal injection for the control of swelling and trismus caused by impacted mandibular third molars extraction.

METHODS:

Cochrane, PUBMED, EMBASE and CBM were searched for eligible studies. Hand-searching included references of the included studies and Chinese dental journals. Risk of bias of the included studies was assessed by two reviewers independently using Cochrane Collaboration's tool, and data extraction was done by them. Meta-analysis was delivered with Revman 5.1.

RESULTS:

Seven randomized controlled trials, involving 684 participants, were included. Six of them had moderate risk of bias and one had high risk of bias. Meta-analysis showed that DM pericoronal injection could relieve trismus by 6.77 mm (P=0.02) within 1-2 days after the surgery. It could also reduce 51% of the risk of moderate-severe trismus(P<0.000 01) and could significantly control facial swelling (P<0.05). There was no differences between 4 mg and 8 mg DM (P>0.05).

CONCLUSION:

Periodontal injection of 4-5 mg DM could control facial swelling and trismus following impacted mandibular third molar extraction. But more randomized controlled trials are needed.

• Authors: Chunjie Li, Hongwei Zhao, Longjiang Li, Shuangjun Li, Yuan Wu, Xuejuan Liao, Jian Pan
• Journal: Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology (Hua Xi Kou Qiang Yi Xue Za Zhi) Vol. 31 Issue 3 Pg. 267-71 (Jun 2013) ISSN: 1000-1182 [Print] China
• PMID: 23841298 (Publication Type: Journal Article, Systematic Review)

Chemical References

• Dexamethasone

Topics

• Dexamethasone
• Edema
• Humans
• Mandible
• Molar, Third
• Pain, Postoperative
• Tooth Extraction
• Tooth, Impacted
• Trismus