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Improvement of calcinosis using pamidronate in a patient with juvenile dermatomyositis.

Abstract
A 7-year-old girl with juvenile dermatomyositis developed severe calcinosis, despite an extensive medication regimen. Three administrations of intravenous pamidronate produced significant improvement in calcinosis, pain and function, leading to remission less than 1 year after induction of therapy.
AuthorsJared Martillotti, Douglas Moote, Lawrence Zemel
JournalPediatric radiology (Pediatr Radiol) Vol. 44 Issue 1 Pg. 115-8 (Jan 2014) ISSN: 1432-1998 [Electronic] Germany
PMID23839717 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Bone Density Conservation Agents
  • Diphosphonates
  • Pamidronate
Topics
  • Bone Density Conservation Agents (therapeutic use)
  • Calcinosis (diagnostic imaging, drug therapy, etiology)
  • Child
  • Dermatomyositis (complications, diagnostic imaging, drug therapy)
  • Diphosphonates (therapeutic use)
  • Female
  • Humans
  • Pamidronate
  • Radiography
  • Treatment Outcome

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