Abstract | BACKGROUND: AIM: To compare the effectiveness of positional therapy versus CPAP on positional OSA. METHODS: Prospective randomized trials were systematically searched from the OVID databases. The trials comparing positional therapy versus CPAP in patients with positional OSA were included. Apnea-hypopnea index (AHI), mean oxygen saturation level, arousal index, sleep efficiency, and sleep time were the outcomes of this meta-analysis. RESULTS: Three crossover trials were identified from Canada, New Zealand, and United States from 1999 to 2010. A total of 71 patients were randomly assigned to receive CPAP or positional therapy and the mean age of patients was 51 y. Positional therapy showed higher AHI (mean difference, MD: 4.28, 95% CI: 0.72-7.83) and lower oxygen saturation level (MD: -1.04, 95% CI: -1.63 to -0.46) than CPAP. It showed no distinct advantage over CPAP in terms of arousal index, sleep efficiency, and total sleep time, but CPAP reduced sleep time in the supine position. CONCLUSION: CPAP is superior to positional therapy in reducing the severity of sleep apnea and increasing the oxygen saturation level in patients with positional OSA.
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Authors | Stanley C N Ha, Hoyee W Hirai, Kelvin K F Tsoi |
Journal | Sleep medicine reviews
(Sleep Med Rev)
Vol. 18
Issue 1
Pg. 19-24
(Feb 2014)
ISSN: 1532-2955 [Electronic] England |
PMID | 23831268
(Publication Type: Comparative Study, Journal Article, Meta-Analysis)
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Copyright | Copyright © 2013 Elsevier Ltd. All rights reserved. |
Topics |
- Continuous Positive Airway Pressure
- Humans
- Posture
(physiology)
- Prone Position
(physiology)
- Randomized Controlled Trials as Topic
- Sleep Apnea, Obstructive
(etiology, physiopathology, therapy)
- Supine Position
(physiology)
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