Abstract |
Treatment of seborrheic dermatitis (SD) is an important issue in dermatology. This study was undertaken to compare efficiency of sertaconazole 2% cream vs. clotrimazole 1% cream for the treatment of seborrheic dermatitis. One hundred twenty eight patients suffering from SD were studied. Patients were randomly divided into two groups. Sixty four patients received local sertoconazole 2% cream and in control group 64 patients received clotrimazole 1% cream. They were recommended to use the cream twice a day for 4 weeks. At the beginning of referring and 2 and 4 weeks after first visit, the patients were examined by a dermatologist to assess improvement of clinical symptoms. The mean age of sertaconazole and clotrimazole group patients was 34.78+/-13.54 and 38.68+/-11.88, respectively. The highest level of satisfaction (87.6%) was observed 28 days after sertaconazole administration and in clotrimazole group it was 50%. Relapse of the disease one month after stopping treatment was not observed in groups treated with sertaconazole 2% cream and clotrimazole 1% cream. This study suggests that sertaconazole 2% cream is an effective and well-tolerated treatment for moderate to severe facial seborrheic dermatitis.
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Authors | Mohamad Goldust, Elham Rezaee, Shahin Rouhani |
Journal | Annals of parasitology
(Ann Parasitol)
Vol. 59
Issue 1
Pg. 25-9
( 2013)
ISSN: 2299-0631 [Print] Poland |
PMID | 23829055
(Publication Type: Journal Article, Randomized Controlled Trial)
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Chemical References |
- Antifungal Agents
- Imidazoles
- Thiophenes
- sertaconazole
- Clotrimazole
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Topics |
- Adult
- Antifungal Agents
(therapeutic use)
- Clotrimazole
(therapeutic use)
- Dermatitis, Seborrheic
(drug therapy)
- Double-Blind Method
- Female
- Humans
- Imidazoles
(therapeutic use)
- Male
- Middle Aged
- Skin Cream
- Thiophenes
(therapeutic use)
- Young Adult
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