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CHD7 in charge of neurogenesis.

Abstract
In this issue of Cell Stem Cell, Feng et al. (2013) report that the gene mutated in human CHARGE syndrome, ATP-dependent chromatin remodeling factor CHD7, contributes to the control of neurogenesis. The authors also report that exercise ameliorates these defects and suggest it as an intervention worthy of study in CHARGE syndrome.
AuthorsKimberly H Kim, Charles W M Roberts
JournalCell stem cell (Cell Stem Cell) Vol. 13 Issue 1 Pg. 1-2 (Jul 03 2013) ISSN: 1875-9777 [Electronic] United States
PMID23827700 (Publication Type: Journal Article, Comment)
CopyrightCopyright © 2013 Elsevier Inc. All rights reserved.
Chemical References
  • Chd7 protein, mouse
  • DNA-Binding Proteins
  • SOXC Transcription Factors
  • Sox11 protein, mouse
  • Sox4 protein, mouse
Topics
  • Animals
  • DNA-Binding Proteins (physiology)
  • Gene Expression Regulation, Developmental
  • Neural Stem Cells (cytology)
  • Neurogenesis (physiology)
  • SOXC Transcription Factors (metabolism)

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