Abstract | BACKGROUND: CASE PRESENTATION: We report a case of a 22-year-old female university student who was admitted to the University Hospital of the West Indies, Jamaica with a presumptive diagnosis of pseudomembranous colitis PMC. She presented with a 5-day history of diarrhoea following clindamycin treatment for coverage of a tooth extraction due to a dental abscess. Her clinical condition deteriorated and progressed from diarrhoea to toxic megacolon, bowel perforation and Gram-negative sepsis. Clostridium difficile NAP12/ribotype 087 was isolated from her stool while blood cultures grew Klebsiella pneumoniae. Despite initial treatment intervention with empiric therapy of metronidazole and antibiotic clearance of Klebsiella pneumoniae from the blood, the patient died within 10 days of hospital admission. CONCLUSIONS:
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Authors | Orville D Heslop, Karen Roye-Green, Kathleen Coard, Michael R Mulvey |
Journal | BMC infectious diseases
(BMC Infect Dis)
Vol. 13
Pg. 299
(Jul 01 2013)
ISSN: 1471-2334 [Electronic] England |
PMID | 23815405
(Publication Type: Case Reports, Journal Article)
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Chemical References |
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Topics |
- Adult
- Clindamycin
(adverse effects)
- Clostridioides difficile
(classification, isolation & purification)
- Community-Acquired Infections
(microbiology)
- Enterocolitis, Pseudomembranous
(microbiology)
- Fatal Outcome
- Female
- Hospitalization
- Humans
- Klebsiella Infections
(microbiology)
- Klebsiella pneumoniae
(isolation & purification)
- Megacolon, Toxic
(microbiology)
- Young Adult
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