Study on the treatment of acute thallium poisoning.

Abstract

BACKGROUND:

Acute thallium poisoning rarely occurs but is a serious and even fatal medical condition. Currently, patients with acute thallium poisoning are usually treated with Prussian blue and blood purification therapy. However, there are few studies about these treatments for acute thallium poisoning.

METHODS:

Nine patients with acute thallium poisoning from 1 family were treated successfully with Prussian blue and different types of blood purification therapies and analyzed.

RESULTS:

Prussian blue combined with sequential hemodialysis, hemoperfusion and/or continuous veno-venous hemofiltration were effective for the treatment of patients with acute thallium poisoning, even after delayed diagnosis.

CONCLUSIONS:

Blood purification therapies help in the clearance of thallium in those with acute thallium poisoning. Prussian blue treatment may do the benefit during this process.

• Authors: Hong-Tao Zhang, Bao-Ping Qiao, Bao-Ping Liu, Xian-Guo Zhao
• Journal: The American journal of the medical sciences (Am J Med Sci) Vol. 347 Issue 5 Pg. 377-81 (May 2014) ISSN: 1538-2990 [Electronic] United States
• PMID: 23811578 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Antidotes
• Ferrocyanides
• Thallium
• ferric ferrocyanide

Topics

• Acute Disease
• Adolescent
• Adult
• Aged
• Alopecia (chemically induced, diagnosis, therapy)
• Antidotes (therapeutic use)
• Child
• Child, Preschool
• Female
• Ferrocyanides (therapeutic use)
• Heavy Metal Poisoning
• Hemoperfusion (methods, statistics & numerical data)
• Humans
• Male
• Middle Aged
• Poisoning (diagnosis, therapy)
• Thallium (poisoning)
• Treatment Outcome