Abstract |
We investigated whether a "yearly" histrelin implant would provide pubertal suppression when left in place for 2 years. Equivalent suppression was observed when comparing 12 and 24 months in 33 children with central precocious puberty. A single implant for 2 years reduces cost and number of implant procedures.
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Authors | Katherine A Lewis, Andrea K Goldyn, Karen W West, Erica A Eugster |
Journal | The Journal of pediatrics
(J Pediatr)
Vol. 163
Issue 4
Pg. 1214-6
(Oct 2013)
ISSN: 1097-6833 [Electronic] United States |
PMID | 23809043
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2013 Mosby, Inc. All rights reserved. |
Chemical References |
- Drug Implants
- Gonadotropin-Releasing Hormone
- Luteinizing Hormone
- histrelin
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Topics |
- Child
- Child, Preschool
- Drug Implants
- Female
- Gonadotropin-Releasing Hormone
(administration & dosage, analogs & derivatives, therapeutic use)
- Humans
- Hypothalamo-Hypophyseal System
(drug effects)
- Luteinizing Hormone
(blood)
- Male
- Puberty, Precocious
(drug therapy)
- Sex Factors
- Time Factors
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