Abstract | BACKGROUND: MATERIALS AND METHODS: RESULTS: On the basis of previous results, specific IgM monoclonal antibodies were produced in BALB/c mice, in order to further improve and extend the immunological approach to the study of bilitranslocase in renal cancer cells as well as to develop its potential diagnostics use. CONCLUSIONS: In this article we show an immunological approach, based on newly developed monoclonal antibodies, to a detailed biochemical and functional characterization of a protein whose gene and protein structure is still unknown. We were able to demonstrate our novel mAb as a tumor marker candidate of renal cell carcinoma, which may prove useful in the diagnostic procedures.
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Authors | Sendi Montanic, Michela Terdoslavich, Uros Rajcevic, Luigina De Leo, Serena Bonin, Vladka Curin Serbec, Sabina Passamonti |
Journal | Radiology and oncology
(Radiol Oncol)
Vol. 47
Issue 2
Pg. 128-37
(Jun 2013)
ISSN: 1318-2099 [Print] Poland |
PMID | 23801909
(Publication Type: Journal Article)
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