[Research progress on proteomics in femur head necrosis].

Abstract

Appearance of proteomics technology can fleetly filt and reveal specificity biomarkers of disease, this will help to reveal the pathogenesis of femur head necrosis and help early diagnosis, find more effective methods and therapeutic targets. At present, they are hot spots that find out the occurred mechanism,related proteins of early diagnosis and early treatment and its functional identification; set up the early related database; optimize the protein extraction methods for research of femur head necrosis. This article reviews the application of study technology of related proteins of femur head necrosis on bone tissue, serum,related animal model,and in order to provide further research ideas.

• Authors: Miao-Feng Hu, Xiao-Cheng Zhou, Le-Tian Shan, Lu-Wei Xiao, Pei-jian Tong
• Journal: Zhongguo gu shang = China journal of orthopaedics and traumatology (Zhongguo Gu Shang) Vol. 26 Issue 3 Pg. 264-6 (Mar 2013) ISSN: 1003-0034 [Print] China
• PMID: 23795453 (Publication Type: English Abstract, Journal Article, Review)

Topics

• Early Diagnosis
• Femur Head Necrosis (diagnosis, metabolism)
• Humans
• Proteomics (methods)