A practice-based randomised controlled trial of the efficacy of three interventions to reduce dentinal hypersensitivity.

Abstract

OBJECTIVES:

The aim of this study was to evaluate the efficacy of three different interventions (non-desensitising toothpaste, desensitising toothpaste and professionally applied dentine bonding agent) in reducing dentinal hypersensitivity over a 2-week, 3-month and 6-month-period in a dental practice setting.

METHODS:

This was a randomised controlled, single-blind; parallel-group trial conducted in general dental practice by a single general dental practitioner. Seventy-five subjects were randomly allocated to three groups; non-desensitising toothpaste (NDT), desensitising toothpaste (DT) and professionally applied desensitising agent (DA). Dentinal hypersensitivity was measured using a Visual Analogue Scale (VAS) to record the response from a standardised short blast of air from a triple syringe. Dentinal hypersensitivity was recorded at baseline, two weeks, three months and six months for all groups.

RESULTS:

Dentinal hypersensitivity reduced significantly (p<0.0001) in both groups DT and DA, in addition the reduction in sensitivity was sustained and continued to improve over a 6-month-period. The greatest reduction in dentinal hypersensitivity was recorded in group DA.

CONCLUSIONS:

The results from this study suggest that application of dentine bonding agents, to teeth diagnosed with dentine hypersensitivity provides the greatest improvement in dentine hypersensitivity at 2 weeks and 6 months. This reduction in dentine hypersensitivity is greater than that achieved by the desensitising toothpaste tested and a non-desensitising toothpaste.

• Authors: M Gibson, M O Sharif, A Smith, P Saini, P A Brunton
• Journal: Journal of dentistry (J Dent) Vol. 41 Issue 8 Pg. 668-74 (Aug 2013) ISSN: 1879-176X [Electronic] England
• PMID: 23791771 (Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
• Copyright: Copyright © 2013 Elsevier Ltd. All rights reserved.

Chemical References

• Complex Mixtures
• Dentin Desensitizing Agents
• Dentin-Bonding Agents
• Potassium Compounds
• Resin Cements
• Seal and Protect resin cement
• Toothpastes
• colgate sensitive
• hydrated silica gel-based toothpaste
• Silicic Acid

Topics

• Adolescent
• Adult
• Aged
• Complex Mixtures (therapeutic use)
• Dentin Desensitizing Agents (therapeutic use)
• Dentin Sensitivity (prevention & control)
• Dentin-Bonding Agents (therapeutic use)
• Female
• Follow-Up Studies
• Humans
• Male
• Middle Aged
• Pain Measurement (methods)
• Potassium Compounds (therapeutic use)
• Resin Cements (therapeutic use)
• Silicic Acid (therapeutic use)
• Single-Blind Method
• Toothbrushing (instrumentation)
• Toothpastes (therapeutic use)
• Treatment Outcome
• Visual Analog Scale
• Young Adult